- Title
- Treatable traits in asthma during pregnancy: a call for a shift towards a precision-based management approach
- Creator
- Joshi, Esha; Gibson, Peter G.; McDonald, Vanessa M.; Murphy, Vanessa E.
- Relation
- European Respiratory Review Vol. 32, Issue 170, no. 230105
- Publisher Link
- http://dx.doi.org/10.1183/16000617.0105-2023
- Publisher
- European Respiratory Society (ERS)
- Resource Type
- journal article
- Date
- 2023
- Description
- Asthma is the most common chronic medical condition in pregnancy. Asthma exacerbations in pregnancy are unpredictable, and are associated with adverse maternal and fetal perinatal outcomes such as preterm birth and low birthweight. Goals of asthma management in pregnancy are to establish effective asthma control and prevent exacerbations. Optimising the management of asthma in pregnancy is an important goal of practice and future research. Treatable traits is a precision medicine paradigm proposed for the management of airways diseases, which holistically addresses the complexity and heterogeneity of airways disease. It is an individualised treatment approach that aims to improve outcomes. This makes treatable traits well suited for pregnant women with asthma, who have a high prevalence of obesity, mental health conditions, poor symptom perception and suboptimal asthma management skills including low treatment adherence. These traits are measurable and treatable. In this review, we explore current knowledge on the burden of asthma, maternal and perinatal consequences of asthma during pregnancy, the treatable traits paradigm, the prevalence of treatable traits in pregnant women with asthma, and consider how the treatable traits paradigm can be integrated into the management of asthma in pregnancy.
- Subject
- asthma; pregnancy; treatable traits; chronic medical conditions
- Identifier
- http://hdl.handle.net/1959.13/1499140
- Identifier
- uon:54622
- Identifier
- ISSN:0905-9180
- Language
- eng
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